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Merck
CN

A55004

4-(2-Aminoethyl)morpholine

99%

Synonym(s):

2-Morpholinoethylamine

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About This Item

Empirical Formula (Hill Notation):
C6H14N2O
CAS Number:
2038-03-1
Molecular Weight:
130.19
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24890978
EC Number:
218-011-6
Beilstein/REAXYS Number:
104378
MDL number:
MFCD00006182

Key Documents

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Product Name

4-(2-Aminoethyl)morpholine, 99%

InChI key

RWIVICVCHVMHMU-UHFFFAOYSA-N

InChI

1S/C6H14N2O/c7-1-2-8-3-5-9-6-4-8/h1-7H2

SMILES string

NCCN1CCOCC1

assay

99%

form

solid

refractive index

n20/D 1.476 (lit.)

bp

205 °C (lit.)

density

0.992 g/mL at 25 °C (lit.)

Quality Level

200

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Application

4-(2-Aminoethyl)morpholine is widely used in biomedical applications as this moiety serves as an important lysosome-targeting group. Some of its applications include:
  • Synthesis of the lysosome-targetable fluorescent probe for hydrogen sulfide imaging in living cells.
  • Synthesis of 1,8-naphthalimide conjugated Troger′s bases as deoxyribonucleic acid (DNA) targeting fluorescent probe.
  • Synthesis of intramolecular charge transfer-photoinduced electron transfer-fluorescence resonance energy transfer (ICT-PET-FRET) fluorescent probe for monitoring pH changes in living cells.
  • It is also used as a precursor to synthesize a variety of antimicrobial agents.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B - Skin Sens. 1

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

186.8 °F - closed cup

flash_point_c

86 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM8427
BCCG2723
BCCF6707
BCCF6708
BCCF6706

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A lysosome-targetable fluorescent probe for imaging hydrogen sulfide in living cells.
Liu T, et al.
Organic Letters, 15(9), 2310-2313 (2013)
Synthesis of some new 1, 2, 4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities.
Bayrak H, et al.
European Journal of Medicinal Chemistry, 44(3), 1057-1066 (2009)
Małgorzata Góra et al.
International journal of molecular sciences, 21(16) (2020-08-17)
The present study aimed to design and synthesize a new series of hybrid compounds with pyrrolidine-2,5-dione and thiophene rings in the structure as potential anticonvulsant and antinociceptive agents. For this purpose, we obtained a series of new compounds and evaluated
Danford Mhule et al.
International journal of pharmaceutics, 550(1-2), 149-159 (2018-08-21)
Stimuli-responsive nano-drug delivery systems can optimize antibiotic delivery to infection sites. Identifying novel lipids for pH responsive delivery to acidic conditions of infection sites will enhance the performance of nano-drug delivery systems. The aim of the present investigation was to
Design, synthesis, and structure? activity relationships of benzophenone-based tetraamides as novel antibacterial agents.
Vooturi S K, et al.
Journal of Medicinal Chemistry, 52(16), 5020-5031 (2009)
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