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A16602

Sigma-Aldrich

DL-N-Acetylhomocysteine thiolactone

98%

Synonym(s):

2-Acetamido-4-mercaptobutyric acid γ-thiolactone

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About This Item

Empirical Formula (Hill Notation):
C6H9NO2S
CAS Number:
Molecular Weight:
159.21
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

powder

mp

109-111 °C (lit.)

SMILES string

CC(=O)NC1CCSC1=O

InChI

1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8)

InChI key

NRFJZTXWLKPZAV-UHFFFAOYSA-N

Application

<ul>
<li><strong>Ultrasonic synthesis of stable oil filled microcapsules:</strong> This study explores the ultrasonic synthesis of oil-filled microcapsules using thiolated chitosan, potentially involving derivatives like N-Acetylhomocysteine thiolactone for improved stability and functional properties. The research provides insights into advanced microencapsulation techniques relevant in pharmaceutical and industrial applications (

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 3 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Comparison of monothiols and vitamin therapy administered alone or in combinations during methylmercury poisoning.
C Bapu et al.
Bulletin of environmental contamination and toxicology, 52(2), 182-189 (1994-02-01)
S M Naqvi et al.
Neuroreport, 2(1), 61-63 (1991-01-01)
The present study was undertaken to evaluate the neurotoxic effects of the organophosphate, phosphamidon, on glutathione-S-transferase (GST) activity and concentration of sulphhydryl groups, and to study the possible protection against these effects by the simultaneous administration of the antioxidant, acetylhomocysteine
N Emonet et al.
Journal of photochemistry and photobiology. B, Biology, 40(1), 84-90 (1997-08-01)
The sensitivity of human dermal fibroblasts to UVA radiation has been linked to a decrease in intracellular glutathione (GSH) levels. GSH (gamma-glutamyl-cysteinyl-glycine) is a radical scavenger and a cofactor for protective enzymes such as selenium-dependent GSH peroxidases. In this study
G Papaccio et al.
Journal of cellular biochemistry, 71(4), 479-490 (1998-11-25)
This study showed that citiolone (CIT), a free radical scavenger, significantly increased superoxide dismutase (P < 0.001 vs. untreated NOD, NMMA-treated, and silica-treated animals), catalase (P < 0.01 vs. untreated NOD), and glutathione peroxidase (P < 0.001 vs. untreated NOD
[Serum sickness type reaction to citiolone].
M Luque Sánchez et al.
Atencion primaria, 16(5), 295-296 (1995-09-30)

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