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G6805

Glycolaldehyde dimer

Name: Glycolaldehyde dimer
Brand: ALDRICH

crystalline, mixture of stereoisomers. Melts between 80 and 90 °C depending on stereoisomeric composition

Synonym(s):

1,4-Dioxane-2,5-diol, 2,5-Dihydroxy-1,4-dioxane, Hydroxyacetaldehyde dimer

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About This Item

Empirical Formula (Hill Notation):

C₄H₈O₄

CAS Number:

23147-58-2

Molecular Weight:

120.10

Beilstein:

506029

MDL number:

MFCD00012133

UNSPSC Code:

12352100

PubChem Substance ID:

24895276

NACRES:

NA.22

Quality Level

200

form

crystalline

storage temp.

2-8°C

SMILES string

OC1COC(O)CO1

InChI

1S/C4H8O4/c5-3-1-7-4(6)2-8-3/h3-6H,1-2H2

InChI key

ATFVTAOSZBVGHC-UHFFFAOYSA-N

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Related Categories

Organic Building Blocks

Application

Glycolaldehyde dimer may be used in the synthesis of 3,4-diaza-2-hexene-1,6-diol, which can undergo hydrogenation to form 1,2-bis(2-hydroxyethyl)hydrazine. It undergoes cycloaddition with 2,3-dihydrofuran in the presence of a chiral catalyst to form fused bicyclic tetrahydrofuran (bis-THF) alcohol, a key moiety of HIV protease inhibitors.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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1, 2-bis (2-hydroxyethyl) hydrazine and derivatives.

Nielsen AT

The Journal of Organic Chemistry, 42(17), 2900-2902 (1977)

Macrocarquinoids A-C, new meroterpenoids from Sargassum macrocarpum.

Hiromi Niwa et al.

Journal of natural medicines, 75(1), 194-200 (2020-09-26)

The production and accumulation of advanced glycation end products (AGEs) have been implicated in diabetes and diabetic complication. This study was conducted as a search for an AGE inhibitor from brown alga, Sargassum macrocarpum. Separation and purification were performed using

Efficient Synthesis of (3 R, 3a S, 6a R)-Hexahydrofuro [2, 3-b] furan-3-ol from Glycolaldehyde.

Canoy WL

Organic Letters, 10(6), 1103-1106 (2008)

Fructosamine-3-Kinase as a Potential Treatment Option for Age-Related Macular Degeneration.

Sander De Bruyne et al.

Journal of clinical medicine, 9(9) (2020-09-10)

Age-related macular degeneration is the leading cause of blindness in the developed world. Since advanced glycation end products (AGEs) are implicated in the pathogenesis of AMD through various lines of evidence, we investigated the potential of fructosamine-3-kinase (FN3K) in the

Aniline-based catalysts as promising tools to improve analysis of carbonyl compounds through derivatization techniques: preliminary results using dansylacetamidooxyamine derivatization and LC-fluorescence.

Stéphan Houdier et al.

Analytical and bioanalytical chemistry, 410(27), 7031-7042 (2018-08-11)

Derivatization techniques based on α-effect amines and H+ catalysis are commonly used for the measurement of carbonyl compounds (CCs), whether in environmental, food, or biological samples. Here, we investigated the potential of aniline-based catalysts to improve derivatization rates of selected

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