96092
N-Z-1,3-Propanediamine hydrochloride
≥98.0% (AT)
Synonym(s):
N-Z-1,3-Diaminopropane hydrochloride, Benzyl N-(3-aminopropyl)carbamate hydrochloride
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About This Item
Recommended Products
Assay
≥98.0% (AT)
form
crystals
reaction suitability
reagent type: cross-linking reagent
mp
185-189 °C
functional group
Cbz
amine
SMILES string
[H]Cl.NCCCNC(OCC1=CC=CC=C1)=O
InChI
1S/C11H16N2O2.ClH/c12-7-4-8-13-11(14)15-9-10-5-2-1-3-6-10;/h1-3,5-6H,4,7-9,12H2,(H,13,14);1H
InChI key
XKMBTMXQMDLSRB-UHFFFAOYSA-N
Other Notes
Building block
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Journal of medicinal chemistry, 37(19), 2991-3007 (1994-09-16)
The aim of this study was the discovery of nonpeptide renin inhibitors with much improved oral absorption, bioavailability, and efficacy, for use as antihypertensive agents. Our prior efforts led to the identification of A-74273 [1,R = 3-(4-morpholino)propyl], with a bioavailability
Journal of medicinal chemistry, 27(3), 325-341 (1984-03-01)
Tri- and tetrapeptide analogues were synthesized and evaluated as renal vasodilators. These peptides were prepared by standard coupling reactions, which also provided good yields with hindered alpha-methyl amino acid derivatives. Preliminary evidence of renal vasodilator activity was determined in anesthetized
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