937185
Polysuccinimide
≥95%, average Mw 60000
Synonym(s):
PSI
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About This Item
Linear Formula:
(C4H3NO2)n
CAS Number:
MDL number:
NACRES:
NA.21
UNSPSC Code:
12352142
Product Name
Polysuccinimide, ≥95%, average Mw 60000
agency
suitable for controlled release
assay
≥95%
form
powder or chunks
mol wt
average Mw 60000
color
white to light brown
application(s)
advanced drug delivery
agriculture
cosmetics
Quality Level
Related Categories
Application
Polysuccinimide (PSI) has been used for a variety of applications including:
- As a nanocarrier or microcarrier delivery vehicle in pharmaceutical, cosmetic, and agriculture (agrochemical) fields
- As electrospun fibers, films, meshes or mats for wound healing applications
- As nanofibers for electronic and biosensor applications
- As a sustainable and environmentally friendly alternative to non-degradable polymers
Features and Benefits
- Biodegradable by hydrolysis allowing for sustained and controlled delivery
- High swelling ratio with superabsorbent properties
- Water soluble
- Peptide-like and biocompatible
General description
Polysuccinimide (PSI), commonly synthesized through thermal polymerization, is a polyimide precursor for the production of such biocompatible and degradable polymers namely polyaspartic acid and various polyaspartamides. Polyaspartic acid is produced by hydrolysis of PSI under alkaline condition while polyaspartamide is produced by ring opening of PSI using a nucleophilic reagent. The presence of amide linkages in these polymers gives them peptide-like structures which is prone to hydrolysis and subsequent degradation. These derivatives could be potential substitutes for different polyamino acids in many medical applications.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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