936111
SerrKap Palladacycle
≥95%
Synonym(s):
[Pd(μ-AcO)(4-Cl-CˆN-SO3Na)]2
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About This Item
Quality Level
Assay
≥95%
form
solid
color
yellow
storage temp.
−20°C
SMILES string
[H]C(C1=C([Pd]23oc(C)o[Pd]4(C5=C(C([H])=[N]4C6=CC=C(S(=O)(O[Na])=O)C=C6)C=CC(Cl)=C5)oc(C)o2)C=C(Cl)C=C1)=[N]3C7=CC=C(S(=O)(O[Na])=O)C=C7
Application
SerrKap Palladacycle is a phosphine-free, water soluble Pd dimer catalyst used extensively for low temperature modifications of nucleosides via Suzuki-Miyaura and Heck reactions. It is also compatible with flow reaction conditions and suitable for late-stage oligonucleotide and DNA modification.
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Description
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Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 4
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
新产品
Certificates of Analysis (COA)
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Current protocols, 2(7), e502-e502 (2022-07-28)
Modification of nucleosides via cross-coupling processes has been carried out extensively on unprotected halonucleosides to produce functionalized nucleosides that are often developed for incorporation into oligonucleotides or used as fluorescent probes. This approach requires protection of the 5'-OH with the
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