934801
Glycidol chitosan
Degree of functionalization > 80%
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Synonym(s):
Dihydroxypropyl chitosan, Glycolchitosan, glycol chitosan
Linear Formula:
[C9H17NO6]n [C8H13NO5]m
UNSPSC Code:
12352201
NACRES:
NA.21
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General description
Chitosan is a cationic biodgradable and biocompatible biopolymer that has been commonly used in many applications. The polymer chains are positively charged when disolved in aqueous solutions of pH<6.5. However, the biomedical applications of the positively charged chitosan are limited becuase it cannot be easily dissolved in aqueous media. Glycidol chitosan is a derivative of chitosan whereby hydrohilic glycidol is grafted onto the amino groups of chitosan to improve its solubility in a wider range of pH. It possesses many useful biological properties such as biocompatibility, biodegradability, and antimicrobial properties. It can also be further functionalized to induce photo and thermally crosslinkable properites and can be used as a precursor for hydrogel preparations that can be used in many biomedical applications.
Application
- Hydrogels
- Tissue engineering
- Bioprinting
- Drug delivery system
Features and Benefits
- Naturally derived biopolymer
- Cationic
- Enhanced solubility
- Tunable precursor material
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Modified chitosan hydrogels as drug delivery and tissue engineering systems: present status and applications
Tapan Kumar Giri
Acta Pharmaceutica Sinica. B, 2 (2012)
Chitosan chemistry and pharmaceutical perspectives
Kumar MR
Chemical Reviews, 104 (2004)
Glycol Chitosan: A Water-Soluble Polymer for Cell Imaging and Drug Delivery
Fengming Lin
Molecules (Basel), 24 (2009)
Evaluation of the biological properties of soluble chitosan and chitosan microspheres
Carreno-Gomez, B
International Journal of Pharmaceutics, 148 (1997)
Effect of chitosan dissolved in different acids on its ability to control postharvest gray mold of table grape
Romanazzi G
Phytopathology, 99(9) (2009)
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