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929646

Sigma-Aldrich

Poly(ethylene glycol) diacrylamide

average MN 10,000, acrylamide, MEHQ as stabilizer

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Synonym(s):
PEG diacrylamide, PEG hydrogel, PEGDAAm, Polyethylene glycol
Linear Formula:
H2CCHC(O)NH(CH2CH2O)n CH2CH2NHC(O)CHCH2
CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.25

form

fine powder

Quality Level

mol wt

Mn 10000
average Mn 10000

contains

MEHQ as stabilizer

color

white to off-white

solubility

deionized water: 20 wt. % at 23 °C

Ω-end

acrylamide

α-end

acrylamide

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General description

Poly(ethylene glycol) (PEG) diacrylamide is a linear, homobifunctional crosslinking PEG polymer with two acrylamide groups. PEG diacrylamide replaces the unstable ester bonds of commonly used PEG diacrylate crosslinkers with hydrolytically stable amides.

Application

PEG diacrylamide is a biocompatible, hydrophilic polymer commonly used to form crosslinked polymer networks and PEG hydrogels. Crosslinked networks can be formed via radical initiator induced polymerization and photopolymerization. Due to its stable amide bond, PEG diacrylamide can be used to prepare hydrogels suitable for long-term studies and eliminate non-specific hydrogel degradation. The acrylamide functional groups can also be reacted with thiol-containing peptide crosslinkers to create enzymatically-sensitive crosslinked networks. PEG diacrylamide has numerous applications in tissue engineering, 3D printing, and drug delivery.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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