Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

923753

Sigma-Aldrich

INVIVO-GEL TGF-β bioink

suitable for 3D bioprinting applications

Sign Into View Organizational & Contract Pricing

Synonym(s):
3D bioprinting, 3DBP, ECM
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

storage temp.

2-8°C

Application

INVIVO-GEL TGF-β bioink is specifically developed and optimized for 3D bioprinting applications. The INVIVO-GEL TGF-β bioink kit includes optimally formulated TGF-mimetic peptide conjugated gelatin-based hydrogel complex packed in syringe for easy dispensing. The kit also includes Gel-linker, which reinforces mechanical stability. A transparent hydrogel forms when contents are properly mixed and exposed to UV light. This bioink is capable of generating mechanically stable 3D structures that can be maintained for days in the culture environment. TGF may promote ECM production, as reported by numerous studies demonstrating the dramatic increase in matrix synthesis and deposition by vascular smooth muscle and endothelial cells when grown on hydrogels with tethered TGF-β.

Components

INVIVO-GEL TGF-β in syringe 5mL x 2
Gel-linker(A) powder 500µL x 1
Gel-linker(B) powder 1µL x 1

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

WGK

WGK 1

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Designing Gelatin Methacryloyl (GelMA)-Based Bioinks for Visible Light Stereolithographic 3D Biofabrication
Kumar H et al.
Macromolecular Bioscience, 11 (2020)
Gelatin methacryloyl and its hydrogels with an exceptional degree of controllability and batch-to-batch consistency
Zhu et al.
Scientific Reports, 9, 6863-6863 (2019)
Synergetic roles of TGF-? signaling in tissue engineering
Lee et al.
Cytokine, 115, 60?63-60?63 (2019)
Shining Xiao et al.
Stem cell reviews and reports, 15(5), 664-679 (2019-06-04)
Gelatin methacrylate (GelMA)-based hydrogels are gaining a great deal of attention as potentially implantable materials in tissue engineering applications because of their biofunctionality and mechanical tenability. Since different natural tissues respond differently to mechanical stresses, an ideal implanted material would
Mengxiang Zhu et al.
Scientific reports, 9(1), 6863-6863 (2019-05-06)
Gelatin methacryloyl (GelMA) is a versatile material for a wide range of bioapplications. There is an intense interest in developing effective chemical strategies to prepare GelMA with a high degree of batch-to-batch consistency and controllability in terms of methacryloyl functionalization

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service