921998
Droplet generator chip - Multi channel design
Fluidic 1032, PC
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Synonym(s):
Microfluidic chip for nanoparticle and microparticle synthesis
NACRES:
NA.23
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description
Microfludic chip x1
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Application
Microfluidic generation of droplets can produce highly monodispersed droplets with high frequency (up to hundreds of kHz). Interest in droplet-based microfluidic systems has grown substantially, because microfluidics offers the ability to handle very small volumes of reagents, provides better mixing, encapsulation, sorting, and sensing. Microfluidics can be used for high throughput experimentation. Microfluidic-based droplets have many applications, including particle synthesis and chemical analysis. Highly controlled droplet production also makes single cell analysis, or drug testing possible.
Droplet generator chip - Multi channel design, Fluidic 1032, PC is made of PC (polycarbonate). This droplet generator chip with three identical droplet generation units of double cross geometry was specifically developed for use in single cell sequencing experiments, where single cells (W) and beads/lysis buffer (W) need to be introduced into a single droplet in an oil phase (O). Fluidic 1032 features Mini Luer interfaces and its use requires a microfluidic pump setup with the ability to control three individual flows. It is, however, also possible to use this droplet generator to generate W/O droplets by simply closing one inlet and supplying only two inlets with a liquid stream.
Droplet generator chip - Multi channel design, Fluidic 1032, PC is made of PC (polycarbonate). This droplet generator chip with three identical droplet generation units of double cross geometry was specifically developed for use in single cell sequencing experiments, where single cells (W) and beads/lysis buffer (W) need to be introduced into a single droplet in an oil phase (O). Fluidic 1032 features Mini Luer interfaces and its use requires a microfluidic pump setup with the ability to control three individual flows. It is, however, also possible to use this droplet generator to generate W/O droplets by simply closing one inlet and supplying only two inlets with a liquid stream.
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Microfluidic-assisted fabrication of carriers for controlled drug delivery.
Santos H A, et al.
Lab on a chip, 17, 1856-1883 (2017)
Sharma T Sanjay et al.
Advanced drug delivery reviews, 128, 3-28 (2017-09-19)
Conventional systematically-administered drugs distribute evenly throughout the body, get degraded and excreted rapidly while crossing many biological barriers, leaving minimum amounts of the drugs at pathological sites. Controlled drug delivery aims to deliver drugs to the target sites at desired
Dongfei Liu et al.
Lab on a chip, 17(11), 1856-1883 (2017-05-10)
The microfluidic technique has brought unique opportunities toward the full control over the production processes for drug delivery carriers, owing to the miniaturisation of the fluidic environment. In comparison to the conventional batch methods, the microfluidic setup provides a range
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Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.
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