920444
mPEG functionalized gelatin
50% PEGylation, PEG average Mn 1k, gel strength 300 g Bloom
Synonym(s):
PEGylated Gelatin, Gelatin / GelMA & derivatives
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About This Item
Linear Formula:
(C32H50N9O12-)m(CH2CH2O)n
NACRES:
NA.23
UNSPSC Code:
12352201
Quality Level
form
(solid or chunk(s) or fiber)
mol wt
PEG average Mn 1k
color
white to off-white
storage temp.
2-8°C
Application
mPEG functionalized gelatin is Type A gelatin grafted with PEG that can be used in drug delivery research. Gelatin is a denatured protein that is obtained by hydrolysis of animal collagen. Its biodegradability, biocompatibility, chemical modification potential and cross-linking possibility make gelatin-based nanoparticles (GNPs) a promising carrier system for drug delivery applications. mPEG functionalization has several advantages − prolonged circulation in the body, decreased degradation by metabolic enzymes, and reduction or elimination of protein immunogencity.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
动物来源培养基
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A novel smart PEGylated gelatin nanoparticle for co-delivery of doxorubicin and betanin: A strategy for enhancing the therapeutic efficacy of chemotherapy.
Ghorbani M, et al.
Materials Science and Engineering, C, 97, 833-841 (2019)
Modified gelatin nanoparticles for gene delivery.
Wettig S D, et al.
Int. J. Pharmacol., 554, 224-234 (2019)
Sajed Amjadi et al.
Materials science & engineering. C, Materials for biological applications, 97, 833-841 (2019-01-27)
Betanin (BET) can reduce the side effects of potent anticancer drugs e.g. doxorubicin (DOX) on the normal tissues in co-administration with them because of the synergistic therapeutic effect and consequently the reduced required amount of anticancer agents. Despite interest in
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 920444-1G | 04065266006520 |