920401
Methoxypolyethylene glycol
average MN 1,000 (by NMR), (Propionic acid), methoxy
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Synonym(s):
O-(2-Carboxyethyl)-O′-methylpolyethylene glycol 1,000, PEG acid, PEG carboxylic acid, Polyethylene glycol, mPEG-COOH, mono-Methyl polyethylene glycol 1′000 propionic acid
Linear Formula:
CH3(OCH2CH2)nOCH2CH2COOH
UNSPSC Code:
12352106
NACRES:
NA.23
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product name
Methoxypolyethylene glycol 1,000 propionic acid,
form
solid
Quality Level
mol wt
average Mn 1,000 (by NMR)
color
white to off-white
Ω-end
(Propionic acid)
α-end
methoxy
polymer architecture
shape: linear
functionality: monofunctional
storage temp.
2-8°C
Related Categories
Application
Methoxypolyethylene glycol 1,000 propionic acid is a pegylation agent used to conjugate proteins to reduce immunogenicity and prolong serum half-life of proteins and enzymes.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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Andrea Fajdetić et al.
European journal of medicinal chemistry, 46(8), 3388-3397 (2011-05-24)
Synthesis, antibacterial activity and pharmacokinetic properties of a novel class of macrolide antibiotics-macrolones-derived from azithromycin, comprising oxygen atom(s) in the linker and either free or esterified quinolone 3-carboxylic group, are reported. Selected compounds showed excellent antibacterial potency towards key erythromycin
A Ton J Dirks et al.
Bioconjugate chemistry, 20(6), 1129-1138 (2009-05-21)
The Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) has recently proven to be a powerful synthetic tool in various fields of chemistry, including protein-polymer conjugation. In this article, we describe a fluorogenic CuAAC, which allows for efficient monitoring of protein-polymer conjugation. We show
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