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Merck
CN

919632

TissueFab® bioink 

(GelHA)ma -UV/365 nm

Synonym(s):

Bioink, HAMA, Hyaluronic acid, Hyaluronic acid methacrylamide, Hyaluronic acid methacrylate, Hyaluronic acid methacryloyl, Sodium hyaluronate

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About This Item

UNSPSC Code:
12352201
NACRES:
NA.23

Key Documents

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Quality Level

100

description

suitable for 3D bioprinting applications

sterility

sterile-filtered

form

viscous liquid

impurities

≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)

color

colorless to pale yellow

particle size

0.2 μm

pH

6.5-7.5

application(s)

3D bioprinting

storage temp.

2-8°C

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Application

TissueFab® - HAMA-UV bioink is a hyaluronic acid methacrylate and GelMA based bioink for 3D bioprinting applications. The formulation is optimized for 3D bioprinting of tissues and constructs using extrusion based 3D bioprinters, and can be can be used to bioprint cell-laden hydrogels in desired shape without any supporting material. The crosslinking of printed structures can be done in one step using UV light for further culture and maturation of cells for tissue engineering and regenerative medicine applications.

Packaging

10 mL in glass bottle

Legal Information

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Regulatory Information

含少量动物源组分生物产品
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Certificates of Analysis (COA)

Lot/Batch Number
MKCP5946

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Michelle T Poldervaart et al.
PloS one, 12(6), e0177628-e0177628 (2017-06-07)
In bone regenerative medicine there is a need for suitable bone substitutes. Hydrogels have excellent biocompatible and biodegradable characteristics, but their visco-elastic properties limit their applicability, especially with respect to 3D bioprinting. In this study, we modified the naturally occurring
Sudhir Khetan et al.
Cryobiology, 90, 83-88 (2019-08-06)
While significant progress has been made in directing the behavior of cells encapsulated within three-dimensional (3D) covalently crosslinked hydrogels, the capacity of these materials to support in situ cryopreservation of cells directly within the gels has not been assessed. Here

Articles

Bioink Selection for 3D Bioprinting

Bioinks enable 3D bioprinting of tissue constructs for drug screening and transplantation; select suitable bioinks for specific tissue engineering.

Recent Advances in 3D-Bioprinting-based Drug Screening

Learn how 3D bioprinting is revolutionizing drug discovery with highly-controllable cell co-culture, printable biomaterials, and its potential to simulate tissues and organs. This review paper also compares 3D bioprinting to other advanced biomimetic techniques such as organoids and organ chips.

3D生物打印生物墨水选择指南

生物墨水可3D生物打印形成功能组织结构，从而应用于药物筛选、疾病建模和体外移植。针对特定组织工程应用选择生物墨水和打印方法。

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