919012
PEI Prime™ linear polyethylenimine
suitable for gene delivery
Synonym(s):
PEI
Sign Into View Organizational & Contract Pricing
All Photos(2)
About This Item
Linear Formula:
(C2H5N . HCl)n
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23
Related Categories
Application
PEI Prime™ is a cationic polymer designed for high-yield, reproducible and scalable drug and gene delivery. As a gene carrier, PEI forms a complex with nucleic acids via electrostatic self-assembly between the negatively charged nucleic acid phosphate groups and positively charged PEI amine groups. Due to this interaction, PEI has been extensively explored as a gene carrier and is one of the most effective synthetic polymers for the delivery of nucleic acids into cells through endocytosis.
PEI Prime™ uses an optimized form of PEI to reduce performance variance and speed process development time. Each batch of PEI Prime™ undergoes triplicate, quantitative performance testing using an SEAP reporter assay. PEI Prime™ is an excellent choice to produce any biologic cost-effectively, including recombinant proteins, antibodies, and viruses.
PEI Prime™ uses an optimized form of PEI to reduce performance variance and speed process development time. Each batch of PEI Prime™ undergoes triplicate, quantitative performance testing using an SEAP reporter assay. PEI Prime™ is an excellent choice to produce any biologic cost-effectively, including recombinant proteins, antibodies, and viruses.
Legal Information
PEI Prime is a trademark of Serochem LLC
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
S M Zou et al.
The journal of gene medicine, 2(2), 128-134 (2000-05-16)
Several nonviral vectors including linear polyethylenimine (L-PEI) confer a pronounced lung tropism to plasmid DNA when injected into the mouse tail vein in a nonionic solution. and results We have optimized this route by injecting 50 microg DNA with excess
L Wightman et al.
The journal of gene medicine, 3(4), 362-372 (2001-09-01)
Efficient gene transfer is a major challenge for non-viral gene therapy. Understanding how non-viral vectors initiate gene expression could lead to the development of new future vectors with enhanced efficacy. Linear or branched polyethylenimine (PEI)/DNA complexes were generated in varying
W T Godbey et al.
Biomaterials, 22(5), 471-480 (2001-02-24)
Poly(ethylenimine) (PEI) was used to transfect the endothelial cell line EA.hy 926, and the secreted levels of three gene products, tissue-type plasminogen activator (tPA), plasminogen activator inhibitor type 1 (PAI-1), and von Willebrand Factor (vWF), were assessed via ELISA. We
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service