917079
PhotoHA™-IRG, methacrylated hyaluronic acid bioink kit, with Irgacure
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Synonym(s):
3D Bioprinting, Bioink, HAMA, Hyaluronic acid
UNSPSC Code:
12352201
NACRES:
NA.23
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description
Methacrylated hyaluronic acid:
Degree of methacrylation: ≥ 45-65%
Quality Level
sterility
sterile; sterile-filtered
mol wt
Mw 100-150 kDa
composition
Product components :
Methacrylated hyaluronic acid (100 mg)
Irgacure photoinitiator (100 mg)
storage temp.
−20°C
Application
PhotoHA™-IRG bioink kit consists of methacrylated hyaluronic acid (HAMA) and Irgacure photoinitiator. Hyaluronic acid is the most abundant glycosaminoglycan in the body being an important component of several tissues throughout the body. While it is abundant in extracellular matrices, hyaluronic acid also contributes to tissue hydrodynamics, movement and proliferation of cells, and participates in a number of cell surface receptor interactions. The photoinitiator consists of Irgacure 2959 to be formulated in methanol (methanol not included), which allows UV crosslinking of the printed structure at 365 nm. PhotoHA™-IRG provides native-like 3D HA gels, and the final gel stiffness can be customized by changing HA concentrations and crosslinking.
Legal Information
PhotoHA is a trademark of Advanced BioMatrix, Inc.
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2
WGK
WGK 3
Regulatory Information
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Michelle T Poldervaart et al.
PloS one, 12(6), e0177628-e0177628 (2017-06-07)
In bone regenerative medicine there is a need for suitable bone substitutes. Hydrogels have excellent biocompatible and biodegradable characteristics, but their visco-elastic properties limit their applicability, especially with respect to 3D bioprinting. In this study, we modified the naturally occurring
Sudhir Khetan et al.
Cryobiology, 90, 83-88 (2019-08-06)
While significant progress has been made in directing the behavior of cells encapsulated within three-dimensional (3D) covalently crosslinked hydrogels, the capacity of these materials to support in situ cryopreservation of cells directly within the gels has not been assessed. Here
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