913650
Polyoxyethylene bis(azide) solution
average Mn 450, 0.1 g/mL in THF
Synonym(s):
O,O′-Bis(2-azidoethyl)polyethylene glycol, PEG-diazide
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About This Item
Linear Formula:
N3(C2H4O)nC2H4N3
UNSPSC Code:
12352125
NACRES:
NA.23
form
liquid
Quality Level
mol wt
PEG ~400 Da
average Mn 450
concentration
0.1 g/mL in THF
color
pale yellow
storage temp.
2-8°C
Related Categories
Application
PEG for cross-linking and used in "click" chemistry reactions. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. Polymer for preparing enzyme conjugates soluble in organic solvents; promising drug carrier.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
Target Organs
Central nervous system, Respiratory system
Supplementary Hazards
WGK
WGK 3
Flash Point(F)
0.5 °F
Flash Point(C)
-17.5 °C
Regulatory Information
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Improving the tensile strength of carbon nanotube yarn via one-step double [2+1] cycloadditions.
H Kim, et al.
Korean Journal of Chemical Engineering, 33(1), 299-304 (2016)
Shao Qiong Liu et al.
Biomaterials, 30(8), 1453-1461 (2008-12-23)
In this study, biodegradable PEG-peptide hydrogels have been synthesized using Click chemistry. A series of Arg-Gly-Asp (RGD) containing peptides were prepared via a solid phase synthesis approach, which were further functionalized with azide to yield peptide azide or peptide diazide.
Tilman Läppchen et al.
European journal of medicinal chemistry, 89, 279-295 (2014-12-03)
Calixarene 0118 is a potent anti-angiogenic agent that effectively inhibited tumor growth in preclinical studies, and is currently being evaluated in a phase I clinical trial. We have designed two close mimetics of calixarene 0118 containing a terminal alkynyl-functional group
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