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Merck
CN

911518

Polyester bis-MPA dendron 8 NHBoc, 1 NHS (core)

generation 3

Synonym(s):

Bis-MPA dendron, NHS-NHBoc dendron

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About This Item

Empirical Formula (Hill Notation):
C103H165N9O48
Molecular Weight:
2297.44
NACRES:
NA.23
UNSPSC Code:
12162002

Key Documents

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Product Name

Polyester bis-MPA dendron 8 NHBoc, 1 NHS (core), generation 3

description

8 NHBoc, 1 NHS (core)

form

solid (Viscous)

mol wt

generation 3

no. Surface Groups

8

color

colorless to white

functional group

(NHS(core))

storage temp.

−20°C

Related Categories

Application

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allows their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers are biocompatible and biodegradable, making them suitable for biomedical applications. The NHBoc-functionalized corona and NHS-functionalized core of this product can be readily used in bioconjugation reactions.

General description

  • Polymer architecture: Dendron
  • End Group Functionality: NHBoc
  • Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX3665
MKCX0208
MKCL8250

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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

Articles

Dendritic Polyester Scaffolds for Drug Delivery

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

New Multi-Dendrimer Platforms for Supramolecular Assembly

Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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