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911178

Sigma-Aldrich

PS-750-M

greener alternative

solution, 3 wt. % in H2O

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Synonym(s):
FI-750-M solution
Linear Formula:
(C2H4O)nC18H33NO3
CAS Number:
UNSPSC Code:
12352200
NACRES:
NA.22

form

liquid

greener alternative product characteristics

Catalysis
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sustainability

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concentration

3 wt. % in H2O

refractive index

n/D 1.3373

density

0.9931 g/mL

greener alternative category

storage temp.

2-8°C

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General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced to increase catalytic efficiency and also acts as an environmentally benign and sustainable amphiphile. Click here for more information.

Application

PS-750-M 3% solution in water is a custom surfactant developed in the Handa lab.
PS-750-M allows for a variety of reactions, including challenging cross-couplings and monofluorination of indoles, to be conducted in water.

WGK

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Micelle-Enabled Palladium Catalysis for Convenient sp2-sp3 Coupling of Nitroalkanes with Aryl Bromides in Water Under Mild Conditions.
Brals J, et al.
ACS Catalysis, 7245-7250 (2017)
Micelle-Enabled Palladium Catalysis for Convenient sp2-sp3 Coupling of Nitroalkanes with Aryl Bromides in Water Under Mild Conditions.
Brals J, et al.
ACS Catalysis, 7(10), 7245-7250 (2017)
Pranjal P Bora et al.
ChemSusChem, 12(13), 3037-3042 (2019-03-06)
Highly selective direct monofluorination of indoles and arenes was developed through an approach that allows site-specific solubility of substrate and fluorine source in the micelle. This approach was highly selective for a broad range of substrates with excellent functional group
Lucie Finck et al.
The Journal of organic chemistry, 83(14), 7366-7372 (2018-02-10)
Using micelles of FI-750-M, visible light, photocatalysts, and inexpensive halogenating reagents, such as N-bromosuccinimide and N-chlorosuccinimde, selective oxyhalogenations of alkynes were achieved in water under very mild conditions. No halogenation at the aromatic rings was detected, and control experiments revealed

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