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Merck
CN

910813

Sigma-Aldrich

mPEG24-NHS

Synonym(s):

Methoxypolyethylene glycol acetic acid N-succinimidyl ester, mPEG NHS

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5 G
CN¥1,411.82
25 G
CN¥6,576.16
100 G
CN¥10,723.17

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5 G
CN¥1,411.82
25 G
CN¥6,576.16
100 G
CN¥10,723.17

About This Item

Empirical Formula (Hill Notation):
C56H107NO29
CAS Number:
Molecular Weight:
1258.44
MDL number:
UNSPSC Code:
43211915
NACRES:
NA.23

CN¥1,411.82


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Assay

95% (HPLC)

form

solid

mol wt

average Mn 1,250 (by NMR)

reaction suitability

reagent type: chemical modification reagent
reactivity: amine reactive

color

white to off-white

Ω-end

NHS ester

α-end

methoxy

polymer architecture

shape: linear
functionality: monofunctional

storage temp.

−20°C

SMILES string

N1(C(=O)CCC1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC

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This Item
D6001D8906D6924
biological source

(Leuconostoc spp)

biological source

bacterial (Leuconostoc mesenteroides)

biological source

synthetic

biological source

bacterial (Leuconostoc mesenteroides)

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

200

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

form

powder

form

powder

form

powder

form

powder

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

room temp

useful pH range

6.0-8 (10 g/L)

useful pH range

6.0-8.0 (1% in water)

useful pH range

6.0-8 (10 g/L)

useful pH range

5.5 - 8.0

Application

Polyethylene glycols (PEGs) are FDA approved hydrophilic polymers. They are non-toxic, non-immunogenic and non-antigenic, and are widely used in a variety of biomedical applications such as bioconjugation, drug delivery, surface functionalization, and tissue engineering. PEG-NHS is an amine reactive PEG that can react to amino groups of lysine(s) on proteins or other biologics; reaction occurs at room temperature in <1hr at pH 7-8. Stable linker between PEG and NHS ester.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

>230.0 °F

Flash Point(C)

> 110 °C


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