910104
Poly(2-(diethylamino)ethyl methacrylate)
average Mn 10,000
Sign Into View Organizational & Contract Pricing
All Photos(2)
Synonym(s):
Hydrophilic, PDEAEMA, pH sensitive, pH-responsive
Linear Formula:
(C10H19NO2)n
UNSPSC Code:
12162002
NACRES:
NA.23
Recommended Products
![N-[3-(Dimethylamino)propyl]methacrylamide 99%, contains MEHQ as inhibitor](/deepweb/assets/sigmaaldrich/product/structures/295/145/6b4aae15-7cb5-4b7b-9c06-8e6d24e50951/640/6b4aae15-7cb5-4b7b-9c06-8e6d24e50951.png)
![Poly[(2-ethyldimethylammonioethyl methacrylate ethyl sulfate)-co-(1-vinylpyrrolidone)] average Mw <1,000,000 by GPC, 20 wt. % in H2O](/deepweb/assets/sigmaaldrich/product/structures/334/533/03fcaede-76a6-4b5a-a992-9565ea1ace4a/640/03fcaede-76a6-4b5a-a992-9565ea1ace4a.png)
form
powder or solid
mol wt
average Mn 10,000 (by NMR)
average Mn 10,000
color
white to faint yellow
PDI
≤1.3 (by GPC)
storage temp.
2-8°C
Related Categories
Application
Poly(diethylaminoethyl methacrylate) is a pH-responsive polymer. pH-Responsive polymers are a group of stimuli-responsive polymers that can respond to solution pH by undergoing structural and property changes such as surface activity, chain conformation, solubility, and configuration. The term “pH-responsive polymers” is commonly used to describe polymers having ionisable acidic or basic residues whose ionization depends on solution pH. The physical properties of the polymer, such as its chain conformation, configuration, and solubility, can be tailored by manipulating the pH or ionic strength. These unique properties of pH responsive polymer systems consequently make them very useful in various applications such as drug delivery, gene delivery, sensors, surfaces, membranes, and chromatography.
pH-sensitive polymer systems combined with nanotechnology could be utilized as an alternative strategy to traditional targeting systems to overcome major problems in current chemotherapy represented by non-specific tissue distribution of the drugs, tumor heterogeneity, and multidrug resistance (MDR) against anticancer drugs.
pH-sensitive polymer systems combined with nanotechnology could be utilized as an alternative strategy to traditional targeting systems to overcome major problems in current chemotherapy represented by non-specific tissue distribution of the drugs, tumor heterogeneity, and multidrug resistance (MDR) against anticancer drugs.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
pH-Responsive polymers
Kocak G, et al.
Polym. Chem., 8, 144-176 (2017)
Jing Xie et al.
Macromolecular rapid communications, 38(23), 1499-1499 (2017-10-05)
Since diabetes mellitus has become one of the most serious threats to human health, researchers have been designing new drugs and developing new technologies to control the blood glucose level (BGL) while improving patient compliance. In addition to the traditional
pH-sensitive polymers for drug delivery.
Huh K M, et al.
Macromolecular Research, 20(3), 224-233 (2012)
Girish Kumar Tripathi et al.
Current drug delivery, 8(6), 667-677 (2012-02-09)
Helicobacter pylori reside in the gastric mucus layer and at the mucus-epithelial cell interface wherein access of antimicrobial drug to the infection site is restricted both from the stomach and from the gastric blood supply. The aim of the present
Cationic Salecan-based hydrogels for release of 5-fluorouracil.
Qi X, et al.
Royal Society of Chemistry Advances, 7, 14337-14347 (2017)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service