909718
2-(Isopropylsulfonyl)-1-phenylpropan-1-one
≥95%
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Empirical Formula (Hill Notation):
C12H16O3S
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Assay
≥95%
form
powder
reaction suitability
reaction type: C-C Bond Formation
mp
56-59 °C
storage temp.
−20°C
Application
2-(Isopropylsulfonyl)-1-phenylpropan-1-one is part of a suite of reagents developed by the Li group for late-stage functionalization of pharmaceutically relevant compounds. The reagents serve as precursors to alkyl radicals generated under light mediated, redox-neutral and catalyst free conditions for use in the Minisci alkylation of aromatics.
related product
WGK
WGK 3
Regulatory Information
新产品
Certificates of Analysis (COA)
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Peng Liu et al.
Journal of the American Chemical Society, 139(40), 14315-14321 (2017-10-03)
The Minisci alkylation is useful to functionalize aromatics via alkyl radical addition. Current approaches to prepare alkyl radicals follow either oxidative or reductive pathways from various functional groups. Developing new strategy beyond these traditional methods remains elusive yet highly significant.
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