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901800

Sigma-Aldrich

Fluorescent nanodiamond

nitrogen vacancy ~3 ppm NV centers, 140 nm avg. part. size, carboxylic acid functionalized, PEG 3000 coated, 1 mg/mL in deionized water

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Synonym(s):
Fluorescent nanoparticles, Nanodiamonds
UNSPSC Code:
12352300
NACRES:
NA.23

form

nanoparticles

composition

nitrogen vacancy, ~3 ppm NV centers

concentration

1 mg/mL in deionized water

avg. part. size

140 nm

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General description

Fluorescent nanodiamond (nitrogen vacancy ~3 ppm NV centers, 140 nm avg. part. size, carboxylic acid functionalized, PEG 3000 coated, 1 mg/mL in deionized water), a biocompatible carbon-based nanomaterial, has interesting properties like excellent photostability, low toxic and facile surface functionalizability. It can be used for a variety of biological applications.

Application

Nanodiamonds (NDs) containing NV color centres exhibit fluorescence in red/near infra-red (NIR) region. The fluorescence in NDs originates from nitrogen vacancies and, unlike quantum dots and organic dyes, NDs do not photobleach. Fluorescent NDs find applications in background-free imaging, flow cytometry, super-resolution imaging etc. Our PEG coated carboxyl functionalized NDs are well suited for attachment of biomolecules using EDC chemistry. The presence PEG spacer on NDs reduces the steric hindrance among the biomolecules.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Nanodiamond-mediated drug delivery and imaging: Challenges and opportunities
V. Vaijayanthimala et al.,
Expert Opinion on Drug Delivery, 12, 1-1 (2014)
Highly Fluorescent Nanodiamonds Protein-Functionalized for Cell Labeling and Targeting
B. Chang et al.,
Advances in Functional Materials, 23, 5737-5737 (2013)
Nanodiamond bioconjugate probes and their collection by electrophoresis
S. C. Hens et al.,
Diamond and Related Materials, 7, 1858-1858 (2008)
Functionality is Key: Recent Progress in the Surface Modification of Nanodiamond
A. Krueger and D. Lang
Advances in Functional Materials, 22, 890-890 (2012)
The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent
Vaijayanthimala V, et al.
Biomaterials, 33(31), 7794-7802 (2012)
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