901699
3-Mercaptopropanyl-N-hydroxysuccinimide ester
>95%
Synonym(s):
NHS ester
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About This Item
Empirical Formula (Hill Notation):
C7H9NO4S
CAS Number:
Molecular Weight:
203.22
UNSPSC Code:
12352005
NACRES:
NA.23
MDL number:
Product Name
3-Mercaptopropanyl-N-hydroxysuccinimide ester, >95%
InChI
1S/C7H9NO4S/c9-5-1-2-6(10)8(5)12-7(11)3-4-13/h13H,1-4H2
SMILES string
SCCC(ON1C(CCC1=O)=O)=O
InChI key
UTBOEPMMEANMPS-UHFFFAOYSA-N
assay
>95%
form
solid or liquid
reaction suitability
reagent type: linker
color
colorless to yellow
functional group
NHS ester
thiol
storage temp.
2-8°C
Application
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an aliphatic, heterobifunctional crosslinking reagent. Due to the functional groups, this material can be used in a multitude of applications, such as the synthesis of protien-polymer conjugates and the synthesis of functionalized quantum dots. In addition to use as a crosslinking agent, this material can also be used to install functional groups post-polymerization. The terminal N-hydroxysuccinimide (NHS) ester can react with amines while the terminal thiol can react with thiols, alkenes, and alkynes. The free thiol can also be used to form self-assembled monolayers (SAMs) on gold surfaces.
3-Mercaptopropanyl-N-hydroxysuccinimide ester can be used in the synthesis of diaminobutane (DAB) based dendrimers for the formation of an ultrafiltration membrane for the removal of heavy metals.
signalword
Warning
hcodes
Hazard Classifications
Flam. Liq. 3
Storage Class
3 - Flammable liquids
wgk
WGK 3
flash_point_f
110.0 °F
flash_point_c
43.33 °C
Regulatory Information
危险化学品
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Characterization of an engineered cellulose based membrane by thiol dendrimer for heavy metals removal
Algarra M, et al.
Chemical Engineering Journal, 253, 472-477 (2014)
Inclusion of thiol DAB dendrimer/CdSe quantum dots based in a membrane structure: Surface and bulk membrane modification
Algarra M, et al.
Electrochimica Acta, 89, 652-659 (2013)
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