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About This Item
Empirical Formula (Hill Notation):
C11H21NO6
CAS Number:
Molecular Weight:
263.29
MDL number:
UNSPSC Code:
51171641
NACRES:
NA.22
Assay
≥95%
form
liquid
reaction suitability
reagent type: linker
density
1.15 g/cm3 (lit.)
functional group
Boc
amine
carboxylic acid
storage temp.
−20°C
SMILES string
OC(COCCOCCNC(OC(C)(C)C)=O)=O
InChI
1S/C11H21NO6/c1-11(2,3)18-10(15)12-4-5-16-6-7-17-8-9(13)14/h4-8H2,1-3H3,(H,12,15)(H,13,14)
InChI key
OMBVJVWVXRNDSL-UHFFFAOYSA-N
Related Categories
Application
This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains two PEG units to help improve solubility.
t-Boc-N-amido-PEG2-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG2-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
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WGK
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Regulatory Information
新产品
Certificates of Analysis (COA)
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