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901215

Sigma-Aldrich

Ephos

≥95%

Synonym(s):

Dicyclohexyl(3-isopropoxy-2′,4′,6′-triisopropyl-[1,1′-biphenyl]-2-yl)phosphane

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About This Item

Empirical Formula (Hill Notation):
C36H55OP
CAS Number:
2118959-55-8
Molecular Weight:
534.80
UNSPSC Code:
12352128
NACRES:
NA.22

Quality Level

100

Assay

≥95%

form

powder or crystals

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings
reagent type: ligand

mp

161-162 °C

functional group

phosphine

Related Categories

Application

Buchwald ligand for Pd-catalyzed C–N cross-coupling between primary amines and aryl
halides to form 2-arylaminooxazoles. Catalyst system was reported with NaOPh (CDS001581).
Ephos can be used as a ligand in the palladium-catalyzed synthesis of 4-arylaminothiazoles and 2-arylaminooxazoles.

Other Notes

Mechanistic Insight Leads to a Ligand That Facilitates the Pd-Catalyzed Formation of 2-(Hetero)Arylaminooxazoles and 4-(Hetero)Arylaminothiazoles

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Mechanistic Insight Leads to a Ligand That Facilitates the Pd?Catalyzed Formation of 2?(Hetero) Arylaminooxazoles and 4?(Hetero) Arylaminothiazoles.
Olsen E P, et al.
Angewandte Chemie (International Edition in English) (2017)

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