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901003

Sigma-Aldrich

Poly(dioxanone-co-L-lactide)

90:10, viscosity 2.0 dL/g 

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Synonym(s):
PDO-PLA, PDS-PLA
Linear Formula:
(C4H6O3)m(C6H8O4)n
UNSPSC Code:
12162002
NACRES:
NA.23

form

chips

feed ratio

p-dioxanone:lactide 90:10±5

color

white to off-white

viscosity

1.5-2.5 dL/g
2.0 dL/g

storage temp.

−20°C

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General description

Poly(dioxanone-co-L-lactide) is a biodegradable copolymer synthesized from the ring-opening polymerization of p-dioxanone and lactide. Due to the ester linkages found in the polymer backbone, these polymers are able to degrade via hydrolysis. With different degrees of aliphatic character, the ratio of the two monomers affects the rate of hydrolysis and therefore the rate of degradation. Other factors that affect the degradation of these materials could include the end application or post-polymerization processing methods.

Application

Poly(dioxanone-co-L-lactide) is a biodegradable copolymer featuring the high strength of poly(dioxanone) and the flexibility of poly(L-lactide) for use in biomedical research applications such as biomedical devices, drug delivery systems, and tissue engineering constructs.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Articles

Main features of p-dioxanone, glycolide and lactide based copolymers

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