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900930

Sigma-Aldrich

6-Azidohexanoic acid

≥95%

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Synonym(s):
6-Azidocaproic acid
Empirical Formula (Hill Notation):
C6H11N3O2
CAS Number:
79598-53-1
Molecular Weight:
157.17
MDL number:
MFCD12406156
UNSPSC Code:
12352200

Assay

≥95%

form

liquid

reaction suitability

reagent type: cross-linking reagent

availability

available only in USA

refractive index

n/D 1.463

solubility

DMF: soluble
DMSO: soluble
THF: soluble
chloroform: soluble
dichloromethane: soluble

density

1.074 g/mL

storage temp.

2-8°C

InChI

1S/C6H11N3O2/c7-9-8-5-3-1-2-4-6(10)11/h1-5H2,(H,10,11)

InChI key

JCORXJUUSVCJEP-UHFFFAOYSA-N

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Application

6-Azidohexanoic acid is a six-carbon saturated fatty acid with an ω-terminal azide group. This building block can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC), forming a stable amide bond. The terminal azide group allows conjugation with compounds containing alkyne groups through a copper(I)-catalyzed cycloaddition reaction, also known as click chemistry. 6-Azidohexanoic acid is useful for crosslinking, synthesis of chemical probes, and other bioconjugation strategies.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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