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Merck
CN

900721

Bovine fibrillar collagen solution

type I, 65 mg/mL, pH 7.0, suitable for biomedical research

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About This Item

CAS Number:
9007-34-5
UNSPSC Code:
12352200

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Product Name

Bovine fibrillar collagen solution, type I, 65 mg/mL, pH 7.0, suitable for biomedical research

biological source

bovine

description

% Denatured: ≤15%
Collagen concentration (by biruret method): 6.0 - 7.0%
Electrophoretic pattern (purity by SDS PAGE): ≤10% collagen faster than alpha.

form

solution

shelf life

24 mo. (from date of manufacture)

concentration

65 mg/mL

impurities

<0.25 EU/mL Endotoxin

pH

7.0-7.6
7.0

storage temp.

2-8°C

Analysis Note

Appearance: White or off-white viscous gel (paste).

Application

Collagen is a major structural protein that provides structure and strength to tissues in the body. Due to its biocompatibility, biodegradability, and high abundance, collagen has been utilized for many applications in biomedical research. Applications of fibrillar collagen may include:
  • Development of collagen-based tissues for skin replacement, bone substitutes, and to generate artificial blood vessels and valves.
  • Drug delivery systems such as sponges for burns/wounds, formulations with liposomes for sustained drug delivery, materials for transdermal drug delivery, and nanoparticles for gene delivery.
  • As collagen scaffolds for research in cancer, electrophysiological protocols, neuron myelination, immunology, and other cell culture applications.

General description

Bovine fibrillar collagen solution is a highly concentrated (65 mg/mL) Type I collagen solution that can easily be diluted as needed with media or buffer solutions. This material features high purity (purification through pepsin treatment) which offers reduced antigenicity with the removal of possible contaminants and is provided at neutral pH (pH 7.0). In vivo, fibrillar collagen degrades in approximately 30 days.

Legal Information

Product of Collagen Solutions.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

动植物来源生物产品
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Certificates of Analysis (COA)

Lot/Batch Number
MKCF7217

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