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900703

Sigma-Aldrich

Methoxy poly(ethylene glycol)-b-poly(L-lactide)

2k-2k

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Synonym(s):
mPEG-b-PLA, mPEG-PLA, mPEG-PLLA
Linear Formula:
HO[CH(CH3)COO]m[CH2CH2O]nCH3
UNSPSC Code:
12352200
NACRES:
NA.23

form

powder

storage temp.

2-8°C

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Application

Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(L-lactide) (PLLA) block. These materials have been used in control release and nanoparticle formulation for drug encapsulation and delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.

WGK

WGK 3


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Injectable biodegradable polymeric system for preserving the active form and delayed-release of camptothecin anticancer drugs.
Mert O, et al.
Royal Society of Chemistry Advances, 2(1), 176-185 (2012)

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