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900662

Sigma-Aldrich

Poly(D,L-lactide-co-glycolide)(85/15)-b-poly(ethylene glycol)-carboxylic acid

5k-13k

Synonym(s):

PLGA-PEG, PLGA-PEG Carboxylic acid diblock copolymer, PLGA-PEG-COOH, PLGA-b-PEG

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About This Item

Linear Formula:
HO(CH(CH3)COO)x(CH2COO)y(CH2CH2O)nH
UNSPSC Code:
12352106
NACRES:
NA.23

Quality Level

form

solid

storage temp.

2-8°C

Related Categories

Application

Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic Poly(lactide-co-glycolide) (PLGA) block, functionalized with a terminal carboxylic acid. These materials have been used in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Additionally, the ratio of lactide to glycolide can be tuned to control rate of degradation. Carboxylic acid termination allows for facile further chemical modification of these materials.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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