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Key Documents

Safety Information

900480

Sigma-Aldrich

Gold nanoparticles

70 nm, NHS ester functionalized, conjugation kit

Synonym(s):

NHS-activated gold nanoparticles

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About This Item

UNSPSC Code:
12141717
NACRES:
NA.23

form

nanoparticles

shelf life

12 mo. at -20 °C (If stored unopened and as specified, are stable for at least 12 months)

packaging

pkg of 1 ea

storage condition

protect from light

particle size

70 nm

λmax

548 nm

functional group

NHS ester

storage temp.

−20°C

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Application

NHS ester functionalized gold nanoparticles conjugation kit (70 nm) can be used in the surface modification of indium tin oxide (ITO) electrodes for potential usage in electrocatalysis and electrochemical sensing.
AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique. It can be potentially used in immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.

Legal Information

Product of CytoDiagnostics, Inc.

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Facile modification of ITO electrodes with functional materials through catalytic grafting of N-hydroxysuccinimidyl-ester-functionalized methallylsilane
Kumar SS, et al.
Electrochemical Communications, 19, 123-126 (2012)
Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 143(9), 1-4 (2020)
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
Li Z, et al.
Journal of Medical Virology, 78, 396-403 (2020)
Immobilization strategy for enhancing sensitivity of immunosensors: L-Asparagine-AuNPs as a promising alternative of EDC-NHS activated citrate-AuNPs for antibody immobilization
Raghav R and Srivastava S
Biosensors And Bioelectronics, 78, 396-403 (2016)
Recent advances in nanoparticle-based lateral flow immunoassay as a point-of-care diagnostic tool for infectious agents and diseases
Banerjee R and Jaiswal A
Analyst, 143(9), 1970-1996 (2018)

Articles

Gold Nanoparticles for Diagnostics

Drs. Fernandes and Baptista discuss gold nanoparticles synthesis and diagnostics regulations, focusing on lateral flow assays.

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