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88345

Sigma-Aldrich

Thiomorpholine hydrochloride

≥98.0% (AT)

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About This Item

Empirical Formula (Hill Notation):
C4H9NS · HCl
CAS Number:
Molecular Weight:
139.65
Beilstein:
3908104
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

≥98.0% (AT)

form

crystals

mp

174-177 °C

functional group

thioether

storage temp.

2-8°C

SMILES string

Cl[H].C1CSCCN1

InChI

1S/C4H9NS.ClH/c1-3-6-4-2-5-1;/h5H,1-4H2;1H

InChI key

QSJAHJYXDRUZMY-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J I Levin et al.
Bioorganic & medicinal chemistry letters, 16(6), 1605-1609 (2006-01-24)
A series of thiomorpholine sulfonamide hydroxamate TACE inhibitors, all bearing propargylic ether P1' groups, was explored. In particular, compound 5h has excellent in vitro potency against isolated TACE enzyme and in cells, oral activity in a model of TNF-alpha production
[Study of antiradiation drugs. I. Synthesis of some mercapto and amino derivatives of thiomorpholine (author's transl)].
F X Chen et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 15(8), 482-488 (1980-08-01)
Upinder Singh et al.
Bioorganic & medicinal chemistry letters, 13(23), 4209-4212 (2003-11-19)
Combinatorial libraries of N-acylated 5-(S)-aminomethyloxazolidinone derivatives of S-oxide and S,S-dioxide tetrahydro-4(2H)-thiopyranyl and thiomorpholine phenyloxazolidinone series have been synthesized on a solid phase and evaluated for antimicrobial activity. Several novel potent leads have been identified, including orally active oxazolidinones with enhanced
N Someswara Rao et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 58(12), 2737-2757 (2002-10-25)
The natural abundance 15N-NMR chemical shifts of selected aliphatic amines, 2-substituted pyridine type compounds, bialicyclic tertiary amines have been measured as a function of the nature of the solvent. In the case of cyclic aliphatic amines, like piperidine, morpholine, piperazine
I T Ermakova et al.
Mikrobiologiia, 77(5), 617-622 (2008-11-14)
A screening of lignin-degrading basidial fungi that can grow in the presence of thiomorpholine derivatives (the mixture of 1,4-perhydrothiazines) has been performed. Strain Bjerkandera adusta VKM F-3477 was shown to have the maximal rate of growth in the presence of

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