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857416

Sigma-Aldrich

(−)-3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine sesquihydrate

99%, for peptide synthesis

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Synonym(s):
α-Methyl-L-DOPA, L-α-Methyl-DOPA
Linear Formula:
(HO)2C6H3CH2C(CH3)(NH2)CO2H · 11/2H2O
CAS Number:
Molecular Weight:
238.24
EC Number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

powder

optical activity

[α]25/D −13°, c = 1 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

>300 °C (lit.)

application(s)

peptide synthesis

SMILES string

O.O.O.C[C@](N)(Cc1ccc(O)c(O)c1)C(O)=O.C[C@](N)(Cc2ccc(O)c(O)c2)C(O)=O

InChI

1S/2C10H13NO4.3H2O/c2*1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6;;;/h2*2-4,12-13H,5,11H2,1H3,(H,14,15);3*1H2/t2*10-;;;/m00.../s1

InChI key

YKFCISHFRZHKHY-NGQGLHOPSA-N

Gene Information

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WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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David A Ostrov et al.
The Journal of clinical investigation, 128(5), 1888-1902 (2018-02-14)
Major histocompatibility (MHC) class II molecules are strongly associated with many autoimmune disorders. In type 1 diabetes (T1D), the DQ8 molecule is common, confers significant disease risk, and is involved in disease pathogenesis. We hypothesized that blocking DQ8 antigen presentation
Sebastiaan P van Kessel et al.
Nature communications, 10(1), 310-310 (2019-01-20)
Human gut microbiota senses its environment and responds by releasing metabolites, some of which are key regulators of human health and disease. In this study, we characterize gut-associated bacteria in their ability to decarboxylate levodopa to dopamine via tyrosine decarboxylases.

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