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Merck
CN

855286

5-Aminouracil

98%

Synonym(s):

5-Amino-2,4-dihydroxypyrimidine, 5-Amino-2,4-pyrimidinediol

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About This Item

Empirical Formula (Hill Notation):
C4H5N3O2
CAS Number:
Molecular Weight:
127.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
213-252-3
Beilstein/REAXYS Number:
127250
MDL number:
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Product Name

5-Aminouracil, 98%

InChI key

BISHACNKZIBDFM-UHFFFAOYSA-N

InChI

1S/C4H5N3O2/c5-2-1-6-4(9)7-3(2)8/h1H,5H2,(H2,6,7,8,9)

SMILES string

NC1=CNC(=O)NC1=O

assay

98%

form

powder

mp

>300 °C (lit.)

Quality Level

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Asmaa M Fahim et al.
Current computer-aided drug design, 16(4), 486-499 (2019-07-11)
In this investigation, 2-cyano-N-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl) acetamide (3) reacts with dimethylformamide dimethyl acetal (DMF-DMA) to afford the corresponding (E)- 2-cyano-3-(dimethylamino)-N-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylam-ide (4) utilizing microwave irradiation. The condensation reactions of acrylamide derivative 4 with hydrazine derivatives obtain pyrazole derivatives 6a and 6b; respectively. The
Paulina Spisz et al.
International journal of molecular sciences, 21(17) (2020-09-05)
Hypoxia-a hallmark of solid tumors-dramatically impairs radiotherapy, one of the most common anticancer modalities. The adverse effect of the low-oxygen state can be eliminated by the concomitant use of a hypoxic cell radiosensitizer. In the present paper, we show that
A González-Fernández et al.
Mutation research, 106(2), 255-264 (1982-12-01)
Chromosome damage induced in root meristems of Allium cepa L. by an 18-h treatment with 5-aminouracil (AU) was enhanced by 2-h pulses with 5 mM caffeine, the most effective pulse being given from the 8th to the 10th h after
Del Campo et al.
Biology of the cell, 95(8), 521-526 (2003-11-25)
In the multinucleate cells induced in Allium cepa L. meristems, the nuclei surrounded by the largest cytoplasm environment complete replication earlier (advanced nuclei), but have a longer G2, than the others (delayed nuclei). Thus, all nuclei break down the nuclear
K K Upadhyay et al.
Talanta, 82(2), 845-849 (2010-07-07)
An interference-free naked-eye recognition of Al(3+) at its micromolar level has been done in 5% aqueous DMSO solution employing a Schiff base 5-[(2-hydroxy-5-nitro-benzylidene)-amino]-1H-pyrimidine-2,4-dione (receptor 1) which is an intramolecular charge transfer (ICT) probe. The pyrimidine and nitrophenyl groups serve as

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