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850624

Sigma-Aldrich

Hydantoin-5-acetic acid

98%

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Synonym(s):
2,4-Dioxoimidazolidine-5-acetic acid, 5-Hydantoinacetic acid, DL-5-(Carboxymethyl)hydantoin
Empirical Formula (Hill Notation):
C5H6N2O4
CAS Number:
Molecular Weight:
158.11
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

powder

mp

214-215 °C (dec.) (lit.)

SMILES string

OC(=O)CC1NC(=O)NC1=O

InChI

1S/C5H6N2O4/c8-3(9)1-2-4(10)7-5(11)6-2/h2H,1H2,(H,8,9)(H2,6,7,10,11)

InChI key

DQQLZADYSWBCOX-UHFFFAOYSA-N

Application

Reactant for synthesis of:
  • Nonfolate compounds as antiparasitic agents inhibiting pteridine reductase
  • 2,4-Azolidinedione-acetic acid derivatives as anticancer agents
  • Anti-inflammatory and analgesic drugs
  • Amides via polystyrene-supported N-hydroxybenxotriazole resin

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Marta Chylińska et al.
Molecules (Basel, Switzerland), 25(16) (2020-08-23)
Current demand for new protective materials ensuring sterility is systematically growing. The purpose of this work was the synthesis of the biocidal N-halamine hydantoin-containing chitosan (CS-CMH-Cl) and characterization of its properties. The functionalization of the chitosan by 5-hydantoinacetic acid substitution

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