81381
Mowiol® 4-88
Mw ~31,000
Synonym(s):
Poly(vinyl alcohol)
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About This Item
Linear Formula:
[-CH2CHOH-]n
CAS Number:
MDL number:
UNSPSC Code:
12352104
NACRES:
NA.23
form
crystals
Quality Level
mol wt
Mw ~31,000
extent of labeling
86.7-88.7 mol% hydrolysis
~630 polymerization
ign. residue
≤0.5%
viscosity
3.5-4.5 mPa.s, 4 % in H2O(20 °C)
InChI
1S/C2H4O/c1-2-3/h2-3H,1H2
InChI key
IMROMDMJAWUWLK-UHFFFAOYSA-N
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General description
Mowiol® is a water soluble hydrocolloid mucoadhesive based on poly (vinyl alcohol). Mowiol® at pH 8.5 has a couple of advantages over other mounting media:
- its a liquid when the sample is mounted and solidifies after several hours, forming a permanent bond between the coverslip and slide
- fluorescence is stable when held in dark and at 4oC.
Application
Mowiol® is used as an embedding medium for preserving stained cell dishes in the study of siRNA array production of HeLa cells. Mowiol® is also reported to be used as a mounting medium in:
Mowiol® may be used as a coating for sensors based on piezoelectric quartz crystals. Another probable use of Mowiol® is during the study of super fluorescence imaging of biocompatible carbon dots.
- design of TSAR and its applications
- detection of the secreted and cytoplasmic fractions of IpaB, IpaC and IpaD by lysozyme permeabilization
- fluorescence recovery after photobleaching (FRAP).
Mowiol® may be used as a coating for sensors based on piezoelectric quartz crystals. Another probable use of Mowiol® is during the study of super fluorescence imaging of biocompatible carbon dots.
Legal Information
Mowiol is a registered trademark of Kuraray Europe GmbH
WGK
WGK 1
Flash Point(F)
No data available
Flash Point(C)
No data available
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Xiaofang Li et al.
Scientific reports, 7(1), 16495-16495 (2017-12-01)
Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer patients is an unsolved issue. Here, we systematically analyzed the aberrant expression patterns of cervical cancer using RNA-Seq data from The Cancer Genome Atlas (TCGA). We incorporated gene profiling
Avgi Tsolou et al.
Life sciences, 232, 116562-116562 (2019-06-16)
Lung cancer is one of the main causes of cancer-related deaths worldwide and radiotherapy is a major treatment of choice. However, radioresistance is a main reason for radiotherapy failure or tumor relapse. Here, we investigated possible mechanisms associated with cancer
Super-resolution fluorescence imaging of biocompatible carbon dots.
Lemenager G, et al.
Nanoscale, 6, 8614-8623 (2014)
Cedric S Tremblay et al.
Nature communications, 9(1), 3535-3535 (2018-09-01)
Pre-leukemic stem cells (pre-LSCs) give rise to leukemic stem cells through acquisition of additional gene mutations and are an important source of relapse following chemotherapy. We postulated that cell-cycle kinetics of pre-LSCs may be an important determinant of clonal evolution
A Kondratskyi et al.
Cell death & disease, 5, e1193-e1193 (2014-04-26)
The growing number of studies suggested that inhibition of autophagy enhances the efficacy of Akt kinase inhibitors in cancer therapy. Here, we provide evidence that ML-9, a widely used inhibitor of Akt kinase, myosin light-chain kinase (MLCK) and stromal interaction
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