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Key Documents

808350

Sigma-Aldrich

TokeOni

Synonym(s):

2-[(1E,3E)-4-[4-(Dimethylamino)phenyl]-1,3-butadien-1-yl]-4,5-dihydro-(4S)-4-thiazolecarboxylic acid hydrochloride salt, AkaLumine-HCl, Soluble NIR emission luciferin

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50 EA
CN¥1,852.91

CN¥1,852.91


Estimated to ship onApril 07, 2025Details


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50 EA
CN¥1,852.91

About This Item

Empirical Formula (Hill Notation):
C16H19ClN2O2S · xHCl
Molecular Weight:
338.85 (free base basis)
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23

CN¥1,852.91


Estimated to ship onApril 07, 2025Details


Request a Bulk Order

form

powder

Quality Level

storage temp.

−20°C

SMILES string

CN(C)C1=CC=C(/C=C/C=C/C2=N[C@@H](C(O)=O)CS2)C=C1.[H]Cl

InChI

1S/C16H18N2O2S.ClH/c1-18(2)13-9-7-12(8-10-13)5-3-4-6-15-17-14(11-21-15)16(19)20;/h3-10,14H,11H2,1-2H3,(H,19,20);1H/b5-3+,6-4+;/t14-;/m1./s1

InChI key

PZCNKVAGZCXXHX-SSRSOBHISA-N

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This Item
BAH136800070WHA10370172WHA10370105
sterility

sterile

sterility

sterile

sterility

non-sterile

sterility

-

packaging

pack of 50 ea

packaging

pack of 50 ea, pkg of (supplied in a tray)

packaging

pkg of 100 ea

packaging

pkg of 100 ea

manufacturer/tradename

Bel-Art H13680-0040

manufacturer/tradename

Bel-Art H13680-0070

manufacturer/tradename

Whatman 10370172, Whatman Article No. 28414772 (US reference)

manufacturer/tradename

Whatman 10370105, Whatman Article No. 28414766 (US reference)

pore size

40 μm porosity

pore size

70 μm porosity

pore size

~3.0 μm (Grade GF 8)

pore size

~3.0 μm (Grade GF 8)

General description

  • Luciferin is a generic term for the light-emitting compound found in organisms that generate bioluminescence.
  • TokeOni is a new NIR emission luciferin analogue having luminescence peak at 670 ~ 680 nm with a peak range in the near-infrared (NIR) region.
  • TokeOni has the enhanced solubility of >10 mg/mL compared to HCl free (0.2 mg/mL).

Application

  • Bioimaging.
  • in vivo imaging.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Synthesis and luminescence properties of biphenyl-type firefly luciferin analogs with a new, near-infrared light-emitting bioluminophore.
Chihiro M, et al.
Tetrahedron, 69(46), 9726-9734 (2013)
Development of simple firefly luciferin analogs emitting blue, green, red and near-infrared biological window light.
Satoshi I, et al.
Tetrahedron, 69(19), 3847-3856 (2013)
Gi Bum Kim et al.
Cell, 179(1), 251-267 (2019-09-21)
In situ transgenesis methods such as viruses and electroporation can rapidly create somatic transgenic mice but lack control over copy number, zygosity, and locus specificity. Here we establish mosaic analysis by dual recombinase-mediated cassette exchange (MADR), which permits stable labeling

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