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Safety Information

805718

Sigma-Aldrich

Poly(L-lactide-block-acrylic acid)

PLLA Mn 4,500, PAA Mn 18,000

Synonym(s):

PLLA-PAA, PLLA-b-PAA

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About This Item

Linear Formula:
C13H25S3(C3H4O2)yC6H9NO(C3H4O2)xH
UNSPSC Code:
12162002
NACRES:
NA.23

form

powder

mol wt

PAA Mn 18,000
PLLA Mn 4,500

PDI

<1.3

storage temp.

2-8°C

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Application

The PLLA-block-PAA is a biocompatible diblock copolymer which forms cylindrical micelles. The PLLA is hydrophobic and a degradable block, and the PAA is hydrophilic. The diblock polymer can be used to form nanoparticles and micelles or scaffolds.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Hyun Jung Jung et al.
Artificial organs, 32(12), 981-989 (2009-01-10)
Interactions between cell and polymer surface have great implications in tissue engineering. In this study, chondrocyte proliferation and matrix production were examined using porous poly(L-lactide) (PLLA) scaffolds that have different surface characteristics. PLLA scaffolds were prepared using a gas-foaming method
Nikos Petzetakis et al.
ACS nano, 7(2), 1120-1128 (2013-02-09)
The spontaneous one-step synthesis of hollow nanocages and nanotubes from spherical and cylindrical micelles based on poly(acrylic acid)-b-polylactide (P(AA)-b-P(LA)) block copolymers (BCPs) has been achieved. This structural reorganization, which occurs simply upon drying of the samples, was elucidated by transmission

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