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805114

Sigma-Aldrich

PLGA microspheres

25 μm average diameter

Synonym(s):

Degradex® PLGA, PLGA Nanoparticles

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About This Item

Linear Formula:
(C3H4O2)x(C2H2O2)y
UNSPSC Code:
12162002
NACRES:
NA.23

form

powder

Quality Level

100

average diameter

25 μm

density

1.3 g/cm3

shipped in

wet ice

storage temp.

−20°C

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General description

Degradex® is made with poly(D,L-lactide-co-glycolide) with an L/G ratio of 50/50 and a Mw of 30,000.
To re-constitute:
  • Remove the product from freezer
  • Wait until temperature rises to the ambient temperature
  • Add DI water or buffer to the container
  • Vortex and sonicate for 5 minutes to ensure the microspheres are well suspended.

Application

Plain PLGA particles for testing system compatibility in drug delivery research. Particles can be used as carriers by attaching drug or biological/chemical entities to particle surface. PLGA particles are used for controlled release, sustained release and targeted drug delivery.

Legal Information

Degradex is a registered trademark of Phosphorex, Inc.

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WGK

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Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Articles

Degradex® Microspheres and Nanoparticles for Drug Delivery Research and Formulation Development

Study on how Degradex® PLGA microspheres and nanoparticles can be used for drug delivery research and formulation development.

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Polymeric antioxidants show promise in drug delivery with superior bioavailability and antioxidant potential.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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