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799106

Sigma-Aldrich

2-Hydroxypropyl methacrylamide

99% (GC)

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Synonym(s):
N-(2-Hydroxypropyl)-2-methyl-prop-2-enamide, N-(2-hydroxypropyl)methacrylamide), HPMA
Empirical Formula (Hill Notation):
C7H13NO2
CAS Number:
21442-01-3
Molecular Weight:
143.18
MDL number:
MFCD00080531
UNSPSC Code:
12162002
PubChem Substance ID:
329768692
NACRES:
NA.23

Quality Level

100

Assay

99% (GC)

form

powder

mp

67.92 °C

density

1.002 g/mL (predicted)

storage temp.

2-8°C

SMILES string

CC(O)CNC(=O)C(C)=C

InChI

1S/C7H13NO2/c1-5(2)7(10)8-4-6(3)9/h6,9H,1,4H2,2-3H3,(H,8,10)

InChI key

OKPYIWASQZGASP-UHFFFAOYSA-N

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Application

Monomers to synthesize biocompetible polymers and copolymers for drug carriers, protein conjugates and hydrogels in biomedical applications.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Jindrich Kopecek et al.
Advanced drug delivery reviews, 62(2), 122-149 (2009-11-19)
The overview covers the discovery of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers, initial studies on their synthesis, evaluation of biological properties, and explorations of their potential as carriers of biologically active compounds in general and anticancer drugs in particular. The focus is on

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