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Sigma-Aldrich

Fluorescent nanodiamond

Nitrogen vacancy ~1.5ppm NV centers, 100 nm avg. part. size, 1 mg/mL in deionized water

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Synonym(s):
Diamond nanopowder, Nanodiamonds
Linear Formula:
C
UNSPSC Code:
12352302
NACRES:
NA.23

form

suspension

Quality Level

100

composition

Nitrogen vacancy, ~1.5ppm NV centers

concentration

1 mg/mL in deionized water

avg. part. size

100 nm

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General description

Fluorescent nanodiamonds (FNDs) can be prepared by subjecting synthetic diamond nanocrystallites to helium ions. FND is biocompatible and its surface can be easily functionalized. It is a very useful tool in bioimaging mainly because the photons emitted from the defect centers of FND upon laser excitation can easily penetrate the tissue. The emission from FNDs is extremely stable. The average size of the FNDs is 100 nm.
In fluorescent nanodiamonds, the nitrogen vacancy centers in the diamond lattice provide the fluorescence; unlike the quantum dots or organic dyes, the color centers in these don′t photobleach or photoblink. These outstanding properties of fluorescent nanodiamonds along with their biocompatibility, large surface area etc. make them promising as bioimaging probes.
Product can be functionalized with carboxylic acid, hydroxyl, ketones, ethers, and/or hydrogen.

Application

Potential uses of FNDs are as in vivo nanoprobe for bioimaging, cell labelling and cell tracking.

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Nanodiamonds for optical bioimaging
Y. Y. Hui, C-L Cheng, and H-C Chang
Journal of Physics D: Applied Physics, 43(37), 374021-374021 (2010)
Highly Fluorescent Nanodiamonds Protein-Functionalized for Cell Labeling and Targeting
B-M Chang, H-S Lin, L-J Su, et al.
Advances in Functional Materials, 23(46), 5737-5745 (2013)
Mass production and dynamic imaging of fluorescent nanodiamonds
Chang YR, et al.
Nature Nanotechnology, 3(5), 284-288 (2008)
The Exocytosis of Fluorescent Nanodiamond and Its Use as a Long-Term Cell Tracker
Fang CY, et al.
Small, 7(23), 3363-3370 (2011)

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