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779873

Sigma-Aldrich

Methyl-β-cyclodextrin

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, ≥98.0% cyclodextrin basis

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Synonym(s):
Cavasol® W7 M Life Science, MβCD, Methyl-beta-cyclodextrin
CAS Number:
128446-36-6
UNSPSC Code:
12352201
NACRES:
NA.22

grade

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

Quality Level

200

Assay

≥98.0% cyclodextrin basis

form

powder

optical activity

[α]/D 154.0 to 156.0°

mol wt

Mw 1310 g/mol

extent of labeling

1.7-1.9 molar substitution

impurities

≤0.10% unsubstituted cyclodextrin
≤0.20% chloride
≤0.50% reducing substances
≤50 ppm volatile organics

ign. residue

≤0.50%

loss

≤5.0% loss on drying

color

white to off-white

mp

180-182 °C (lit.)

absorption

≤0.10 at 350-600 nm in solution at 10%
≤1.00 at 220-350 nm in solution at 10%

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

InChI key

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

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Application

Methyl-β-cyclodextrin is a macrocyclic compound that can form inclusion complexes with a number of guest molecules. It shows higher solubility in aqueous solutions and greater solubilizing and complexing power compared to the parent β-cyclodextrin. MβCD can be used to enhance the enzyme activity and enantioselectivity of subtilisin enzyme in organic solvents.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
For R&D Use

Legal Information

Cavasol is a registered trademark of Wacker Chemie AG

WGK

WGK 3

Flash Point(F)

368.6 °F

Flash Point(C)

187 °C

Certificates of Analysis (COA)

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Preparation and solid-state characterization of inclusion complexes formed between miconazole and methyl-?-cyclodextrin.
Ribeiro A
Aaps Pharmscitech, 9(4), 1102-1109 (2008)
Improved enzyme activity and enantioselectivity in organic solvents by methyl-?-cyclodextrin.
Griebenow K
Journal of the American Chemical Society, 121(36), 8157-8163 (1999)
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Sara Rodríguez-Acebes et al.
The Biochemical journal, 420(2), 305-315 (2009-03-06)
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