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Merck
CN

778877

4-Azidobenzoic acid solution

~0.2 M in tert-butyl methyl ether, ≥95.0% (HPLC)

Synonym(s):

9-Azidobenzoic acid solution

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About This Item

Empirical Formula (Hill Notation):
C7H5N3O2
CAS Number:
Molecular Weight:
163.13
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1950876
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Product Name

4-Azidobenzoic acid solution, ~0.2 M in tert-butyl methyl ether, ≥95.0% (HPLC)

InChI

1S/C7H5N3O2/c8-10-9-6-3-1-5(2-4-6)7(11)12/h1-4H,(H,11,12)

SMILES string

OC(C1=CC=C(N=[N+]=[N-])C=C1)=O

InChI key

PQXPAFTXDVNANI-UHFFFAOYSA-N

assay

≥95.0% (HPLC)

form

liquid

concentration

~0.2 M in tert-butyl methyl ether

impurities

≤2.0% water

storage temp.

2-8°C

Quality Level

Application

Review

General description

4-Azidobenzoic acid is an aromatic azide generally used in copper(I)-catalyzed azide-alkyne cycloaddition reactions.

signalword

Danger

Hazard Classifications

Flam. Liq. 2 - Skin Irrit. 2 - STOT RE 2

target_organs

Blood

Storage Class

3 - Flammable liquids

wgk

WGK 3

Regulatory Information

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Y Ito et al.
Biotechnology progress, 12(5), 700-702 (1996-09-01)
Photoreactive insulin was synthesized by coupling with azidobenzoic acid. The insulin derivative was immobilized onto the wells of polystyrene culture plates by photoir-radiation. The photoimmobilized insulin enhanced the growth of anchorage-dependent cells such as Chinese hamster ovary CHO-K1 and mouse
Hirokazu Hasuda et al.
Biomaterials, 26(15), 2401-2406 (2004-12-09)
Photoreactive pullulan was prepared, the polymer was photoimmobilized on polymeric or organic surfaces, and its interactions with a protein and a cell type were investigated. The photoreactive pullulan was synthesized by a coupling reaction with 4-azidobenzonic acid. Surface modification was
Todd A Rickett et al.
Biomacromolecules, 12(1), 57-65 (2010-12-07)
Restoring continuity to severed peripheral nerves is crucial to regeneration and enables functional recovery. However, the two most common agents for coaptation, sutures and fibrin glues, have drawbacks such as inflammation, pathogenesis, and dehiscence. Chitosan-based adhesives are a promising alternative
Renxun Chen et al.
Biofouling, 25(6), 517-524 (2009-05-02)
Infection associated with implanted biomaterials is common and costly and such infections are extremely resistant to antibiotics and host defenses. Consequently, there is a need to develop surfaces which resist bacterial adhesion and colonization. The broad spectrum synthetic cationic peptide
Lu Sun et al.
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 23(2), 370-374 (2006-05-19)
Grafting of poly (ethylene glycol) (PEG) on the surface of polysulfone (PSF) sheets by simultaneous or sequential UV irradiation with 4-azidobenzoic acid as the photocoupler was carried out. Water contact angle measurements showed that there was a great improvement of

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