All Photos(1)
Synonym(s):
1-[(Dimethylamino)(morpholino)methylene]-1H-[1,2,3]triazolo[4,5-b]pyridine-1-ium 3-oxide hexafluorophosphate, N-methyl-N-[4-morpholinyl(3-oxido-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl)methylene]methanaminium, hexafluorophosphate
Empirical Formula (Hill Notation):
C12H17F6N6O2P
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Quality Level
Assay
99%
form
powder
mp
218 °C (decomposition)
application(s)
peptide synthesis
storage temp.
2-8°C
SMILES string
CN(C)[C+](N1CCOCC1)N2N=[N+]([O-])C3=C2C=CC=N3.F[P-](F)(F)(F)(F)F
InChI
1S/C12H17N6O2.F6P/c1-15(2)12(16-6-8-20-9-7-16)17-10-4-3-5-13-11(10)18(19)14-17;1-7(2,3,4,5)6/h3-5H,6-9H2,1-2H3;/q+1;-1
InChI key
ILBQIVNHGIVQOQ-UHFFFAOYSA-N
Application
Peptide coupling agent with increased coupling efficiency and lower racemization compared to HATU.
WGK
WGK 3
Regulatory Information
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Peter C Belafsky et al.
The Laryngoscope, 126(1), 108-112 (2015-07-23)
Chronic laryngitis (CL) is common and costly. One of the most common causes of CL is thought to be laryngopharyngeal reflux, although a significant percentage of individuals fail to get better with acid suppressive therapy. The role of other potential
Ayman El-Faham et al.
Organic letters, 9(22), 4475-4477 (2007-09-29)
A novel proton acceptor coupling reagent shows superiority to those described previously. The oxygen in the carbocation moiety confers more solubility to the reagent. Furthermore, it enhances coupling yields and decreases racemization, allowing the use of 1 equiv of base.
Rui Duan et al.
Journal of chromatography. A, 1609, 460510-460510 (2019-09-14)
In this study, a novel phenyl-boronic acid polymeric monolith (PBAPM) in polyether ether ketone (PEEK) tube was fabricated. The inner wall of PEEK tube was modified with mussel inspired polydopamine layer to firmly bond PBAPM, so as to avoid the
Jennifer L Russell et al.
ACS applied materials & interfaces, 9(48), 42075-42083 (2017-11-14)
Inverse opals made by polymerizing vinyl monomers inside a colloidal crystal have lattice dimensions that are contracted relative to the original hard template. This effect was studied in order to investigate the possibility of making double replicas of varying pore
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