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772453

Sigma-Aldrich

Fmoc-Lys(palmitoyl)-OH

95%

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Synonym(s):
Palmitoyl lysine
Empirical Formula (Hill Notation):
C37H54N2O5
CAS Number:
1301706-55-7
Molecular Weight:
606.84
MDL number:
MFCD08274507
UNSPSC Code:
12352209
PubChem Substance ID:
329767567
NACRES:
NA.26

Quality Level

100

Assay

95%

form

powder or crystals

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

71-83 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCC(=O)NCCCC[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C37H54N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-26-35(40)38-27-20-19-25-34(36(41)42)39-37(43)44-28-33-31-23-17-15-21-29(31)30-22-16-18-24-32(30)33/h15-18,21-24,33-34H,2-14,19-20,25-28H2,1H3,(H,38,40)(H,39,43)(H,41,42)/t34-/m1/s1

InChI key

DQZCUQJUXKWZEE-UUWRZZSWSA-N

Related Categories

Application

Amino acid-lipid conjugate for the solid phase synthesis of peptide-lipids. Lipidated peptides have been shown in some cases to lead to increased cellular permeability and metabolic stability.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Joanne T Blanchfield et al.
Journal of medicinal chemistry, 46(7), 1266-1272 (2003-03-21)
The alpha-conotoxin MII is a two disulfide bridge containing, 16 amino acid long peptide toxin isolated from the marine snail Conus magus. This toxin has been found to be a highly selective and potent inhibitor of neuronal nicotinic acetylcholine receptors
Grzegorz Bulaj et al.
Journal of medicinal chemistry, 51(24), 8038-8047 (2008-12-05)
Galanin is an endogenous neuropeptide that modulates seizures in the brain. Because this neuropeptide does not penetrate the blood-brain barrier, we designed truncated galanin analogues in which nonessential amino acid residues were replaced by cationic and/or lipoamino acid residues. The

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