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Quality Level
Assay
≥97.0% (GC)
form
powder
impurities
≤1% water
mp
137-141 °C
SMILES string
C1CN(CCN1)c2ccncc2
InChI
1S/C9H13N3/c1-3-10-4-2-9(1)12-7-5-11-6-8-12/h1-4,11H,5-8H2
InChI key
OQZBAQXTXNIPRA-UHFFFAOYSA-N
Gene Information
rat ... Chrnb2(54239)
Related Categories
General description
1-(4-Pyridyl) piperazine (or 4-Piperazinopyridine) is an active structural component that is used as a building block to prepare various medicinally important active molecules.
Application
1-(4-Pyridyl) piperazine can be used as a building block for the synthesis of:
- Nocathiacin I analogs for antibacterial studies.
- 4-amino-pyridyl derivatives, benzimido isoquinoline based derivatives and tert-pentylphenoxyalkyl piperazine derivatives for various biological applications.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
新产品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl) piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl) amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist.
Journal of Medicinal Chemistry, 48(6), 1857-1872 (2005)
N ε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure?Activity Relationships, and Pharmacokinetic Profiling.
Journal of Medicinal Chemistry, 61(10), 4528-4560 (2018)
Polymethacrylates containing a 4-amino-pyridyl derivative covalently attached as effective catalysts in acylation chemistry: self-activation by neighboring group effects
Polymer International, 64(12), 1685-1689 (2015)
Synthesis, characterization, and bioactivity of new bisamidrazone derivatives as possible anticancer agents.
Medicinal Chemistry Research, 27(5), 1419-1431 (2018)
Benzimidazo [2, 1-a] benz [de] isoquinoline-7-one-12-carboxylic acid based fluorescent sensors for pH and Fe3+
Journal of Photochemistry and Photobiology A: Chemistry, 314(12), 52-59 (2016)
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