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Merck
CN

765457

Gold nanoparticles

10 nm diameter, carboxylic acid functionalized, PEG 3000, OD 50, dispersion in H2O

Synonym(s):

Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid

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About This Item

NACRES:
NA.23
UNSPSC Code:
12162002

Key Documents

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Product Name

Gold nanoparticles, 10 nm diameter, carboxylic acid functionalized, PEG 3000, OD 50, dispersion in H2O

material

PEG 3000

form

dispersion in H2O
nanoparticles

packaging

glass bottle of 1 mL

OD

50

diameter

10 nm

pH

6.0-8.0 (25 °C)

solubility

water: miscible

density

1.00 g/cm3

λmax

520 nm

functional group

carboxylic acid

storage temp.

2-8°C

Quality Level

100

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Application

Carboxylic acid functionalized, PEG 3000, OD 50, and H2O dispersed gold nanoparticles (10 nm) (AuNPs) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy. AUNPs may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.
The carboxylic acid group binds with various proteins and is used in targeted drug delivery and gene therapy.

General description

Carboxylic acid functionalized GNPs form conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW8305
MKCP7677
MKCM4667
MKBZ8814V
MKBN9349V

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Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 6, 1-4 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

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