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Sigma-Aldrich

Gold nanoparticles

50 nm diameter, amine functionalized, PEG 5000 coated, OD 50, dispersion in H2O

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Synonym(s):
Gold nanoparticles NH2 functionalized, Au NP NH2, Gold Colloid
UNSPSC Code:
12162002
NACRES:
NA.23

material

PEG 5000

Quality Level

form

dispersion in H2O
nanoparticles

packaging

poly bottle of 1 mL

OD

50

diameter

50 nm

pH

6.0-8.0 (25 °C)

solubility

water: miscible

density

1.00 g/cm3

λmax

535 nm

functional group

amine

storage temp.

2-8°C

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General description

Amine functionalized GNPs which has Poly Ethylene Glycol (PEG) as the ligand or carrier molecule forms a conjugate with siRNA and is extremely useful in RNAi technology.

Application

Functionalized particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.
Gold nanoparticles 50 nm diameter, amine functionalized, PEG 5000 coated, OD 50, dispersion in H2O can be used in the activation of silica nanosphere for the decomposition of formic acid. It may be used in the radiosensitization and imaging of cancer cells.
AuNPs can be potentially immobilized on antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Gold nanoparticles for radiosensitizing and imaging of cancer cells
Borran AA, et al.
Radiation Physics and Chemistry, 152(25), 137-144 (2018)
Strong metal-molecular support interaction (SMMSI): amine-functionalized gold nanoparticles encapsulated in silica nanospheres highly active for catalytic decomposition of formic acid
Yadav M, et al.
Journal of Materials Chemistry, 22(25), 12582-12586 (2012)
Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 152(25), 1-4 (2020)
Scott H Brewer et al.
Langmuir : the ACS journal of surfaces and colloids, 21(20), 9303-9307 (2005-09-21)
The interaction of bovine serum albumin (BSA) with gold colloids and surfaces was studied using zeta-potential and quartz crystal microbalance (QCM) measurements, respectively, to determine the surface charge and coverage. The combination of these two measurements suggests that BSA binding
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

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