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763934

Sigma-Aldrich

5-Nitrofuran-2-acrylic acid

95%

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Synonym(s):
β-(5-Nitro-2-furyl)acrylic acid, 3-(5-Nitro-2-furanyl)-2-propenoic acid, 5-Nitrofuranacrylic acid
Empirical Formula (Hill Notation):
C7H5NO5
CAS Number:
Molecular Weight:
183.12
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

95%

form

solid

mp

238-240 °C

SMILES string

OC(=O)\C=C\c1ccc(o1)[N+]([O-])=O

InChI

1S/C7H5NO5/c9-7(10)4-2-5-1-3-6(13-5)8(11)12/h1-4H,(H,9,10)/b4-2+

InChI key

LWOWNIPZHGWKNR-DUXPYHPUSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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S Baláz et al.
Chemico-biological interactions, 55(1-2), 93-108 (1985-10-01)
Mutagenic effects of 10 N-alkylamides of 3-(5-nitro-2-furyl)-acrylic acid were assessed in two strains of Salmonella typhimurium TA100 (rfa+ and rfa-). Experimental data were confronted with physiologically based compartment model comprising passive membrane transport, metabolical inactivation in cytoplasm and formation of
G Kellová et al.
Folia microbiologica, 29(1), 23-34 (1984-01-01)
The effect of 18 newly synthesized esters and amides of 3-(5-nitro-2-furyl)acrylic acid on bacteria (Escherichia coli, Staphylococcus aureus), yeasts (Saccharomyces cerevisiae, Candida albicans), molds (Aspergillus niger, Penicillium cyclopium, Rhizopus oryzae) and algae (Chlorella pyrenoidosa, Euglena gracilis, Scenedesmus obliquus) was investigated.
S N Chatterjee et al.
Chemico-biological interactions, 63(2), 185-194 (1987-01-01)
5-Nitro-2-furylacrylic acid (5-NFA) caused dose dependent inhibition of growth of Escherichia coli K-12 strain AB 2480 (uvr-, rec-), the 37% (D37) and 10% (D10) survival doses being 1.0 microgram/ml.h and 1.75 micrograms/ml.h, respectively. Although much higher doses of drug were
E Sturdík et al.
Chemico-biological interactions, 53(1-2), 145-153 (1985-02-01)
Mutagenicity of three selected series of 2-furylethylene was determined by the Ames test. These included: nine alkylesters and eleven N-alkylamides of 5-nitro-2-furylacrylic acid (NFAA) and ten derivatives differing not only at exocyclic double bond, but also in the position 5
E Sturdík et al.
Chemico-biological interactions, 58(1), 69-78 (1986-04-01)
The SOS-function-inducing activities of 36 furylethylenes were characterized in Escherichia coli K12. The induction of the SOS function was assayed by monitoring the beta-galactosidase activity in the sulA::lacZ fusion strain PQ 37. To correct for the inhibitory effects of test

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