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747319

Sigma-Aldrich

Iron oxide(II,III), magnetic nanoparticles solution

10 nm avg. part. size (TEM), PEG functionalized, 1 mg/mL Fe in H2O, dispersion

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Synonym(s):
Fe NP PEG, FexOy, Magnetic iron oxide nanocrystals, Magnetite, Superparamagnetic iron oxide nanoparticles
Empirical Formula (Hill Notation):
Fe3O4
CAS Number:
Molecular Weight:
231.53
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.23

form

dispersion
nanoparticles

Quality Level

concentration

1 mg/mL Fe in H2O

magnetization

>45 emu/g, at room temperature; under 4500 Oe

color

brown

avg. part. size

10 nm (TEM)

density

0.996 g/mL at 25 °C
~1 g/mL at 25 °C

functional group

PEG

storage temp.

2-8°C

SMILES string

O=[Fe].O=[Fe]O[Fe]=O

InChI

1S/3Fe.4O

InChI key

SZVJSHCCFOBDDC-UHFFFAOYSA-N

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General description

Concentration 5mg/ml includes total weight nanocrystals plus ligands.

Application

These magnetic nanoparticles are typically used in imaging or as contrast agents. The surface functionality allows for different ligation or further functionalization.

Do not freeze.

Legal Information

Product of Ocean Nanotech; LLC.

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Simultaneous delivery of multiple therapeutic agents is of great importance for effective chemotherapy due of its well-known drug synergism and suppression to chemoresistance. We report a new theranostic nanoformulation to shuttle multiple chemotherapeutic agents for successfully exterminating cancer cells. This
Tianyuzi Li et al.
International journal of nanomedicine, 10, 3779-3790 (2015-06-18)
Regimen adherence, systemic toxicities, and limited drug penetrance to viral reservoirs are obstacles limiting the effectiveness of antiretroviral therapy (ART). Our laboratory's development of the monocyte-macrophage-targeted long-acting nanoformulated ART (nanoART) carriage provides a novel opportunity to simplify drug-dosing regimens. Progress
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Journal of computer assisted tomography, 38(4), 571-573 (2014-04-16)
Ferumoxytol is a parenteral iron therapy that the Food and Drug Administration recently approved for the treatment of iron-deficiency anemia. The form of the iron, ultrasmall superparamagnetic iron oxide nanoparticles, causes T1, T2, and T2* shortening on magnetic resonance imaging
Anna Lohße et al.
Journal of bacteriology, 196(14), 2658-2669 (2014-05-13)
Biosynthesis of bacterial magnetosomes, which are intracellular membrane-enclosed, nanosized magnetic crystals, is controlled by a set of >30 specific genes. In Magnetospirillum gryphiswaldense, these are clustered mostly within a large conserved genomic magnetosome island (MAI) comprising the mms6, mamGFDC, mamAB
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Journal of chromatography. A, 1395, 173-179 (2015-04-14)
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